Chiara Borsari

Institution: University of Basel

Address:

Department of Biomedicine, University of Basel, Mattenstrasse 28,CH-4058 Basel

Email: chiara.borsari@unibas.ch

Phone: +41612075139

Research interests:

Small molecules drug discovery for cancer therapy. Development of PI3K/mTOR inhibitors.

Selected publications:

5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology. Beaufils F, Cmiljanovic N, Cmiljanovic V, Bohnacker T, Melone A, Marone R, Jackson E, Zhang X, Sele A, Borsari C, Mestan J, Hebeisen P, Hillmann P, Giese B, Zvelebil M, Fabbro D, Williams RL, Rageot D, Wymann MP. J Med Chem. 2017 Sep 14;60(17):7524-7538. doi: 10.1021/acs.jmedchem.7b00930.

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